ISR RELATED

Plenty of rheum to improve

President of the Irish Society for Rheumatology (ISR) Dr Sinéad Harney spoke to Catherine Reilly ahead of the Society’s Spring Meeting and outlined some pivotal issues affecting the specialty Members of the Irish Society for Rheumatology (ISR) gathered recently in Dublin for its Spring Meeting, which is a key event in the Society’s calendar. The…

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Results of study suggest siblings of patients with rheumatoid arthritis are at increased risk of acute coronary syndrome

The results of a study presented at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate an increased risk of acute coronary syndrome (ACS) in siblings of individuals with rheumatoid arthritis (RA), suggesting shared susceptibility between the two diseases. Recent studies have demonstrated that severity of RA is associated with the risk of ACS, suggesting…

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Gout in the elderly linked to higher risk of dementia

The results of a US study presented at EULAR 2018 suggest that gout is associated with a 17-to-20 per cent higher risk of dementia in the elderly. The study included 1.23 million Medicare beneficiaries, of which 65,325 had incident dementia. In an analysis, which was adjusted for various potential confounding variables, including demographics, comorbidities and…

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Combining NSAIDs and TNF inhibitors may reduce radiographic progression in ankylosing spondylitis

The results of a cohort study presented at EULAR 2018 showed that, in patients with ankylosing spondylitis (AS) taking TNF inhibitors, the addition of non-steroidal anti-inflammatory drugs (NSAIDs) was associated with significantly less radiographic progression in a dose-related manner at four years. When looking at specific NSAIDs, celecoxib in combination with TNF inhibitor use was…

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Positive clinical advances in systemic lupus erythematosus

The results of two studies presented at EULAR 2018 demonstrate exciting advances for individuals suffering from systemic lupus erythematosus (SLE). The first is a phase 2 clinical study of a promising oral treatment, baricitinib. The second demonstrates the effective use of the shingles vaccine in SLE patients who are particularly prone to this infection. “Novel…

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Early, intensive treatment of RA provides long-term benefits and may normalise mortality rates — long-term follow-up study

The results of a 23-year, follow-up study presented at the European League Against Rheumatism (EULAR) Annual Congress 2018 suggest early, intensive treatment of rheumatoid arthritis (RA) has long-term benefits including the normalisation of mortality to levels consistent with the general population. “We know that the adverse effects of rheumatoid arthritis on the body only become…

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NSAIDs shown to have causal role in cardiovascular risk of patients with osteoarthritis

The results of a study presented at EULAR 2018 suggest that over two-thirds of the increased cardiovascular risk associated with osteoarthritis is linked to the use of non-steroidal anti-inflammatory drugs (NSAIDs), a mainstay of treatment for this condition. Recent research suggests that osteoarthritis is an independent risk factor for cardiovascular disease (CVD) and several mechanisms…

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