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Iron deficiency anaemia

Iron deficiency anaemia is a major cause of morbidity and burden of disease worldwide, but can generally be diagnosed by blood testing and remedied by iron replacement therapy using the oral or intravenous route Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease. It affects approximately two billion people worldwide,…

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The pathways to better skin disease treatments

Attendees at UCD’s Charles Institute Seminar Series heard a presentation by Dr Vivek T Natarajan on the behaviourof melanocytes in conditions such as vitiligo, melasma and melanoma The Charles Institute, Ireland’s national dermatology research and education centre, hosts a range of guest speakers who cover a variety of topics ranging from skin cancer to psoriasis,…

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Exercise prescription for Parkinson’s – how the little details make BIG impacts

Advances in exercise specificity are having a direct impact on clinical signs and features of Parkinson’s disease CASE REPORT A 51-year-old male presented for a clinical exercise prescription (August 2020), having been referred by his consultant neurologist. The patient was diagnosed with Parkinson’s disease (PD) in August 2017. In the years preceding diagnosis, commonly referred…

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Motor neurone disease in focus

There are approximately 400 people living with MND in Ireland at any one time and an averageof 150 new cases of this rare, incurable disease are diagnosed annually. Motor neurone disease (MND) is a rare, progressive, life-limiting disorder for which there is no cure, and the rate of progression varies greatly from person to person.…

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Apps failing to detect rare skin cancers

A new study has found that a direct-to-consumer machine learning model for detecting skin cancers incorrectly classified rare and aggressive cancers, such as Merkel cell carcinoma (MCC) and amelanotic melanoma, as low-risk. The findings suggest that making apps based on such models available directly to the public without transparency on performance metrics for rare, but…

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Working to create a brighter future for pancreatic cancer patients

Real research progress is now being made for this difficult to treat cancer, including in Ireland Almost two years ago, just before Christmas, I had one of those conversations with a patient of mine, which I really would have liked to postpone, or better yet, not have at all. Monica had pancreatic cancer and had…

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Role of FT-PET in metastatic melanoma

An Australian research team has observed positive long-term outcomes in a majority of patients with metastatic melanoma treated with anti-PD1-based therapy who remain progression-free at one-year by RECIST (Response Evaluation Criteria in Solid Tumours)/ clinical grounds, and particularly in 75 per cent of patients who achieve a complete metabolic response (CMR) on FDG-PET. The study…

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Diagnosis and management of prostate cancer

Prostate cancer accounts for 30 per cent of all newly-diagnosed cases of cancer in Irish men Prostate cancer is the second most frequent cancer diagnosed in men and the fifth leading cause of death globally. Excluding non-melanoma skin cancer, prostate cancer is the leading cause of cancer in men internationally. In 2018, 1,276,106 new cases…

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Respiratory syncytial virus (RSV) infection: An overview

Respiratory syncytial virus (RSV) is a common, ubiquitous and contagious viral pathogen that infects the respiratory tract of most children by two years of age. RSV is an RNA pneumovirus of the Paramyxoviridae family, and humans arethe only natural host. RSV is primarily a childhood infection; however, it may occur at any age and can…

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From bench to bedside in vitiligo

Attendees at UCD’s Charles Institute Seminar Series heard a presentation by Prof Karin U Schallreuter of the Universityof Bradford and University of Greifswald on the current understanding of vitiligo The Charles Institute, Ireland’s national dermatology research and education centre, hosts a range of guest speakers who cover a variety of topics ranging from skin cancer…

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