Clinical News

Management of GORD

An overview of the latest diagnostic and therapeutic approaches to gastroesophageal reflux disease Gastroesophageal reflux disease (GORD) is a common condition affecting up to 20 per cent of the population. The main symptom is a burning sensation in the mid sternum region commonly described as heartburn.  Other symptoms are chest pain, which can mimic a…

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Osteoporosis: What you need to know

A clinical overview of the diagnosis, treatment and management of osteoporosis A person will develop osteoporosis when more bone is lost than is formed. This results in low bone mass and compromised bone strength, with an increased risk of fracture. The majority of these fractures are preventable. The most common bones to fracture are the…

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Being overweight linked to psoriatic arthritis

The results of a study presented at EULAR 2019 demonstrate significant correlation between body mass index (BMI) and disease severity in psoriatic arthritis (PsA). Although PsA has been associated with an enhanced prevalence of obesity and being overweight, few studies have assessed the relationship between weight and the severity of disease in these patients. Results…

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Gout: Challenges and opportunities in diagnosis and management

Dr Rachel Cole and Prof Geraldine McCarthy discuss optimum gout management Case report A 72-year-old man was admitted to hospital in March 2019 with heart failure secondary to new onset atrial fibrillation. He had a past history of hypertension and chronic kidney disease (CKD) stage 3. He had had one episode of acute first metatarsophalangeal…

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Clinical update on the treatment of rheumatoid arthritis

Dr Catherine Sullivan outlines the latest treatment options in rheumatoid arthritis Rheumatoid arthritis (RA) is a common inflammatory arthritis with a prevalence of 1 per cent worldwide. Left untreated it results in irreversible deformity and disability, there is also now ample evidence that delays in diagnosis and treatment results in poorer outcomes. The incidence of…

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No benefit from pazopanib in advanced renal cell carcinoma after metastasectomy

No improvement in disease-free survival (DFS) with adjuvant pazopanib (a VEGF tyrosine kinase inhibitor) was observed for patients with no evidence of disease following metastasectomy for renal cell carcinoma (RCC) when compared with placebo, according to results of a phase 3 trial presented at the 2019 ASCO Annual Meeting. Although effective targeted therapy has become…

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Immunotherapy in metastatic or recurrent cervical cancer

Dr Dearbhaile Collins outlines the latest trial data on immunotherapies for cervical cancer The National Cancer Registry Ireland records 262 new cases of invasive cervical cancer in Ireland each year. This is predominantly a disease of younger women, with over 47 per cent of patients under the age of 45 years old at diagnosis. Squamous…

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The introduction of robotic prostate surgery at Galway University Hospitals

The introduction of robotic surgery in GUH is a major benefit for prostate patients, writes Mr Paddy O’Malley In July of last year the first robotic-assisted radical prostatectomy was performed on a patient at Galway University Hospitals (GUH) by Mr Paddy O’Malley, Consultant Urologist and specialist in robotic surgery, GUH. This was a cumulative effort…

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Migraine research in focus

Priscilla Lynch presents a round-up of recent topical international research in the area of migraine Migraines may increase risk of pregnancy complications Women with migraine and their offspring have greater risks of several adverse pregnancy outcomes than women without migraine, according to the findings of a new study published in Headache. The Danish study investigated…

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The ‘nitty gritty’ of treating the acute migraine attack

Dr Mary Kearney discusses the latest treatment approaches to acute migraine attacks Migraine classification was initiated by the International Headache Society in the early 1990s. It has been reviewed and defined more accurately since that time and in 2018, the third edition of International Headache Disorders was published. It clearly defines migraine with and without…

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