Clinical News

Managing urinary tract infections

An overview of the latest management approaches to UTIs in Ireland, highlighting the importance of antimicrobial stewardship Urinary tract infection (UTI) is the collective term used to describe infections involving any part of the urinary tract, which includes the kidneys, ureters, bladder and urethra. Infections of the bladder (cystitis) and urethra (urethritis) are known as…

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Paediatric urology: A subspecialty born from collaboration

An overview of the opportunities and challenges in the field of paediatric urology Paediatric urology is an often misunderstood and overlooked field of surgery. Paediatric urologists are the custodians of the entire urological and genital systems for both boys and girls, specialising in both the surgical and medical issues related to the kidneys, bladder, and…

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NSAIDs and cardiovascular risk

An outline of the current evidence linking NSAIDs to cardiovascular issues The links between non-steroidal anti-inflammatory drugs (NSAIDs) and cardiovascular (CV) risk has been established for some time. The initial studies on rofecoxib were published in 2000 followed shortly afterwards by other studies showing increased cardiovascular risk. In September 2004, Merck voluntarily withdrew rofecoxib from…

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Onwards and upwards in cardiology

President of the Irish Cardiac Society Prof Jim Crowley spoke with Pat Kelly ahead of the Society’s upcoming Annual Scientific Meeting and AGM about the past, present and future of cardiac care in Ireland The Irish Cardiac Society (ICS) Annual Scientific Meeting and AGM will see a range of distinguished speakers and marks the 70th…

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Early diagnosis of COPD

The early diagnosis of COPD has a significant potential to benefit patients and reduce costs to the health service Perhaps unsurprisingly the best place to start a discussion on the benefits of early diagnosis and treatment in chronic obstructive pulmonary disease (COPD) is with the definition of COPD from the Global Initiative for Chronic Obstructive…

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Addison’s disease

An overview of the clinical manifestations of Addison’s disease, with diagnosis and treatment guidance Addison’s disease (AD), often referred to as primary adrenal insufficiency or hypoadrenalism, is a rare endocrine disorder which occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, aldosterone. The disease is characterised by…

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A look at the current rare disease landscape in Ireland

Rare diseases in Ireland — what’s happening? In 2014, the Department of Health finally published the long-awaited first National Rare Disease Plan for Ireland 2014-2018. The vision of the plan was that “people with rare diseases receive timely access to the best possible evidence-based, patient-centred and family-centred screening (as appropriate), diagnosis, treatment and care through…

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Newborn bloodspot screening for inborn metabolic disorders

Current Irish perspectives on expanded newborn bloodspot screening for inborn metabolic disorders in Ireland All newborns in Ireland are currently screened via the ‘heel-prick test’ at 72-120 hours after birth for six inborn metabolic disorders (IMDs), as well as congenital hypothyroidism and cystic fibrosis. Other countries screen for many more IMDs, using a similar amount…

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A round-up of some of the most topical research presented at this year’s ESC

Cardiovascular disease is biggest killer globally but cancer overtakes in some countries Cardiovascular disease remains the main cause of death globally, but cancer has overtaken it to become the leading cause of death in some high-income and upper-middle-income countries, according to the late-breaking results from the PURE study, which were presented in a Hot Line…

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Evidence-based approaches to hypertension

A comparison of current European and US guidelines and management principles An estimated 1.13 billion people worldwide have hypertension. It is a major cardiovascular risk factor and a leading risk factor for global deaths. According to the World Health Organisation (WHO), in 2015, one-in-four men and one-in-five women had hypertension and fewer than one-in-five people…

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